Intermittent "error occurred while making the HTTP request" - httpclient

Question

error occurred while making the HTTP request
I have a c# client that calls a remote endpoint using a HttpClient. The client is hosted on a Windows Server.
The client will run fine for a long time and then I encounter a "error occurred while making the HTTP request".
We do use Trend Micro AntiVirus.
I run this client about every 5 minutes. It works very well when it starts but when the error happens it keeps happening. To resolve it I shut the service down, wait awhile and then restart it.
Here is my code snippet:
ServicePointManager.SecurityProtocol = SecurityProtocolType.Tls | SecurityProtocolType.Tls11 | SecurityProtocolType.Tls12 | SecurityProtocolType.Ssl3;
System.Net.ServicePointManager.MaxServicePointIdleTime = 10000;
using (var client = new HttpClient())
{
client.BaseAddress = new Uri(URL);
client.DefaultRequestHeaders.Accept.Clear();
client.DefaultRequestHeaders.Accept.Add(new System.Net.Http.Headers.MediaTypeWithQualityHeaderValue("application/json"));
client.DefaultRequestHeaders.ConnectionClose = true;
HttpResponseMessage response = await client.PostAsync(URL, content);
}
Here is the error:
Exception: System.Net.Http.HttpRequestException: An error occurred while sending the request. ---> System.Net.WebException: The underlying connection was closed: An unexpected error occurred on a send. ---> System.IO.IOException: Unable to read data from the transport connection: An established connection was aborted by the software in your host machine. ---> System.Net.Sockets.SocketException: An established connection was aborted by the software in your host machine
at System.Net.Sockets.Socket.EndReceive(IAsyncResult asyncResult)
at System.Net.Sockets.NetworkStream.EndRead(IAsyncResult asyncResult)
Any help would be appreciated.
Thanks!